Dupa chemistry
WebMar 30, 2015 · The DUPA–indenoisoquinoline conjugate exhibited an IC50in the low nanomolar range in 22RV1 cell cultures and induced a complete cessation of tumor growth with no toxicity, as determined by loss of body weight and death of treated mice. Supporting Information ARTICLE SECTIONS Jump To Abstract Introduction Drug Design Synthesis … WebDupa merupakan apa-apa jenis bekas yang digunakan bagi membakar setanggi.Bekas-bekas ini berlainan saiz, bentuk, dan bahan yang digunakan. Ia mungkin terdiri dari mangkuk tanah liat sederhana atau pasu api hingga kepada bekas perak atau emas, dari bekas atas meja kecil setinggi beberapa sentimeter sahaja hingga ke beberapa meter …
Dupa chemistry
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WebFeb 1, 2024 · 2-[3-(1,3-Dicarboxypropyl)ureido] pentanedioic acid (DUPA) is a ligand of PSMA that can selectively attach imaging and therapeutic agents to prostate cancer cells … WebNational Center for Biotechnology Information
WebAbstract In a proof-of-concept study, solid phase synthesis allowed the rapid generation of a small molecule drug conjugate in which the glutamate carboxypeptidase II (GCPII) targeting small molecule DUPA was conjugated to the alkylating subunit of the potent cytotoxin duocarmycin SA. WebProximity-induced chemistry allows for the selective reaction between a functional group and a specific natural residue (e.g. lysine, cysteine, serine) of proteins through the …
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